New publications

Newly-made cells repair myelin more efficiently than ones that survive myelin loss

Newly-made cells repair myelin more efficiently than ones that survive myelin loss

Better understanding remyelination will help us to improve the treatments of myelin diseases, such as MS. We directly compared surviving and newly-made oligodendrocytes in a new zebrafish model of myelin damage, showing that new oligodendrocytes have a much greater capacity for remyelination than survivors. Therefore, our study suggests that the best strategy to promote myelin repair is to boost the production and remyelination capacity of new oligodendrocytes.